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Health Reports. Alzhiemers. Arthritis. Schizophreia.
Health Reports. Alzhiemers. Arthritis. Schizophreia.
Alzheimers Relief,Safe,Inexpensive.
You can buy at your local Pharmacy,it has been safely used for 60 years.
Now being used for Alzheimers. May also improve normal memory
function. So effective even the mainstream researchers are impressed by
results.
Niacinamide or also know as Vitamin B3.
Amount to take. Start off with 500 mg. dose taken after main meal & you
can build up gradually to maximum 1,000 mg three times a day. If you start
to feel nauseous,cut back to 500 mg, three times daily & you should feel
OK again.
You can buy at your local Pharmacy,it has been safely used for 60 years.
Now being used for Alzheimers. May also improve normal memory
function. So effective even the mainstream researchers are impressed by
results.
Niacinamide or also know as Vitamin B3.
Amount to take. Start off with 500 mg. dose taken after main meal & you
can build up gradually to maximum 1,000 mg three times a day. If you start
to feel nauseous,cut back to 500 mg, three times daily & you should feel
OK again.
http://www.sciencedaily.com/releases/2008/11/081104180926.htm
Vitamin B3 Reduces Alzheimer's Symptoms, Lesions: Clinical Trial
On Nicotinamide or (Niacinamide) as it is known in the United Kingdom.
Effect In Alzheimer's Patients.
ScienceDaily (Nov. 5, 2008) — An over-the-counter vitamin in high doses
prevented memory loss in mice with Alzheimer's disease, and UC Irvine
scientists now are conducting a clinical trial to determine its effect in
humans.
Nicotinamide, a form of vitamin B3, lowered levels of a protein called
phosphorylated tau that leads to the development of tangles,one of two
brain lesions associated with Alzheimer's disease.
The vitamin also strengthened scaffolding along which information travels in
brain cells, helping to keep neurons alive and further preventing symptoms in
mice genetically wired to develop Alzheimer's.
"Nicotinamide has a very robust effect on neurons," said Kim Green,
UCI scientist and lead author of the study. "Nicotinamide prevents loss
of cognition in mice with Alzheimer's disease, and the beauty of it is we
already are moving forward with a clinical trial."
Nicotinamide is a water-soluble vitamin sold in health food stores.It generally is
safe but can be toxic in very high doses.
Clinical trials have shown it benefits people with diabetes complications and has
anti-inflammatory properties that may help people with skin conditions.
Nicotinamide belongs to a class of compounds called HDAC inhibitors, which
have been shown to protect the central nervous system in rodent models of
Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis.
Clinical trials are underway to learn whether HDAC inhibitors help ALS and
Huntington's patients.
In the nicotinamide study, Green and his colleague, Frank LaFerla,
added the vitamin to drinking water fed to mice. They tested the
rodents' short-term and long-term memory over time using water-maze
and object-recognition tasks and found that treated Alzheimer's mice
performed at the same level as normal mice, while untreated
Alzheimer's mice experienced memory loss.
The nicotinamide, in fact, slightly enhanced cognitive abilities in normal
mice. "This suggests that not only is it good for Alzheimer's disease, but
if normal people take it, some aspects of their memory might improve,"
said LaFerla, UCI neurobiology and behavior professor.
Scientists also found that the nicotinamide-treated animals had dramatically
lower levels of the tau protein that leads to the Alzheimer's tangle lesion. The
vitamin did not affect levels of the protein beta amyloid, which clumps in the
brain to form plaques, the second type of Alzheimer's lesion.
Nicotinamide, they found, led to an increase in proteins that strengthen
microtubules, the scaffolding within brain cells along which information
travels. When this scaffolding breaks down, the brain cells can die.
Neuronal death leads to dementia experienced by Alzheimer's patients.
"Microtubules are like highways inside cells. What we're doing with nicotinamide
is making a wider, more stable highway," Green said. "In Alzheimer's disease,
this highway breaks down. We are preventing that from happening."
For more info go to .
http://www.sciencedaily.com/releases/2008/11/081104180926.htm
Vitamin B3 Reduces Alzheimer's Symptoms, Lesions: Clinical Trial
On Nicotinamide or (Niacinamide) as it is known in the United Kingdom.
Effect In Alzheimer's Patients.
ScienceDaily (Nov. 5, 2008) — An over-the-counter vitamin in high doses
prevented memory loss in mice with Alzheimer's disease, and UC Irvine
scientists now are conducting a clinical trial to determine its effect in
humans.
Nicotinamide, a form of vitamin B3, lowered levels of a protein called
phosphorylated tau that leads to the development of tangles,one of two
brain lesions associated with Alzheimer's disease.
The vitamin also strengthened scaffolding along which information travels in
brain cells, helping to keep neurons alive and further preventing symptoms in
mice genetically wired to develop Alzheimer's.
"Nicotinamide has a very robust effect on neurons," said Kim Green,
UCI scientist and lead author of the study. "Nicotinamide prevents loss
of cognition in mice with Alzheimer's disease, and the beauty of it is we
already are moving forward with a clinical trial."
Nicotinamide is a water-soluble vitamin sold in health food stores.It generally is
safe but can be toxic in very high doses.
Clinical trials have shown it benefits people with diabetes complications and has
anti-inflammatory properties that may help people with skin conditions.
Nicotinamide belongs to a class of compounds called HDAC inhibitors, which
have been shown to protect the central nervous system in rodent models of
Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis.
Clinical trials are underway to learn whether HDAC inhibitors help ALS and
Huntington's patients.
In the nicotinamide study, Green and his colleague, Frank LaFerla,
added the vitamin to drinking water fed to mice. They tested the
rodents' short-term and long-term memory over time using water-maze
and object-recognition tasks and found that treated Alzheimer's mice
performed at the same level as normal mice, while untreated
Alzheimer's mice experienced memory loss.
The nicotinamide, in fact, slightly enhanced cognitive abilities in normal
mice. "This suggests that not only is it good for Alzheimer's disease, but
if normal people take it, some aspects of their memory might improve,"
said LaFerla, UCI neurobiology and behavior professor.
Scientists also found that the nicotinamide-treated animals had dramatically
lower levels of the tau protein that leads to the Alzheimer's tangle lesion. The
vitamin did not affect levels of the protein beta amyloid, which clumps in the
brain to form plaques, the second type of Alzheimer's lesion.
Nicotinamide, they found, led to an increase in proteins that strengthen
microtubules, the scaffolding within brain cells along which information
travels. When this scaffolding breaks down, the brain cells can die.
Neuronal death leads to dementia experienced by Alzheimer's patients.
"Microtubules are like highways inside cells. What we're doing with nicotinamide
is making a wider, more stable highway," Green said. "In Alzheimer's disease,
this highway breaks down. We are preventing that from happening."
For more info go to .
http://www.sciencedaily.com/releases/2008/11/081104180926.htm
All health info,is provided for
information only & may not
be construed as medical
advise. Readers should
consult their health
professionals on any health
matter relating to their or
their families health.
Info is gathered from
reputable sources,but
readers who fail to consult
with appropriate health
professionals,assume the
risk of any injuries.
The publisher is not
responsible for errors or
omissions.
information only & may not
be construed as medical
advise. Readers should
consult their health
professionals on any health
matter relating to their or
their families health.
Info is gathered from
reputable sources,but
readers who fail to consult
with appropriate health
professionals,assume the
risk of any injuries.
The publisher is not
responsible for errors or
omissions.
Arthritus. The same dose as above.
Can show improvements in just 3 or 4 weeks,as long as you keep taking
vitamin B3 .(Niacinamide.)
Can show improvements in just 3 or 4 weeks,as long as you keep taking
vitamin B3 .(Niacinamide.)
Schizophrenia. Try the same dose as above.
Vitamin B3. has been used since the 1950's. Dr Abram Hoffer
(considered to be the "father" of Orthomolecular Psychiatry)
started using Niacinamide for schizophrenia along with Vitamin C.
He found that if patients started taking both Vitamins within 5 years
of being diagnosed, they had a 66 per cent or higher chance of
recovery. They also needed to continue (Niacinamide) indefinitely.
Vitamin B3. has been used since the 1950's. Dr Abram Hoffer
(considered to be the "father" of Orthomolecular Psychiatry)
started using Niacinamide for schizophrenia along with Vitamin C.
He found that if patients started taking both Vitamins within 5 years
of being diagnosed, they had a 66 per cent or higher chance of
recovery. They also needed to continue (Niacinamide) indefinitely.
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revolutionary new products for optimum healthy living.
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